Short Total Synthesis of the Marine Alkaloid Subarine
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چکیده
منابع مشابه
Total Synthesis of a Marine Alkaloid—Rigidin E
In the present paper, we report an efficient total synthesis of a marine alkaloid, rigidin E. The key tetrasubstituted 2-amino-3-carboxamidepyrrole intermediate was synthesized by cascade Michael addition/intramolecular cyclization between N-(2-(4-(benzyloxy)phenyl)-2-oxoethyl)methanesulfonamide and 3-(4-(benzyloxy)phenyl)-2-cyano-N-methylacrylamide. Subsequent carbonylation with triphosgene ca...
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ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2009
ISSN: 0036-8709
DOI: 10.3797/scipharm.0901-14